What to know about alpha-gal syndrome, the life-threatening meat allergy caused by tick bites (opens original article in a new tab)

Alpha-gal syndrome, a life-threatening meat allergy caused by tick bites, is increasing in prevalence due to expanding tick habitats and heightened awareness. The condition triggers allergic reactions to mammal meats and dairy, with treatment focusing on avoidance and new therapies like the FDA-approved drug Xolair.

• Alpha-gal syndrome is a life-threatening meat allergy caused by tick bites, triggered by the sugar alpha-gal found in mammal meat and tick saliva.
• The condition is rising due to increased awareness and expanding habitats of lone star ticks, with 450,000 estimated cases in the U.S.
• The FDA approved Xolair in 2024 for severe allergic reactions, while avoiding mammal meats and tick bites is critical for management.